Dissertation Topics

Mechanobiology of Stem Cells and Nucleus

Sturctual & Molecular Biochemistry

Nuclear lamins regulate oxidative homeostasis in health and disease.
Nucleus mechanotransduction: applied mechanical forces stabilize the nuclear lamina and direct cell fate decision making.
Mapping matrix directed protein interactome of A-type lamins using genetic code expansion.
Single-cell analysis of matrix-directed differentiation of mesenchymal stem cells.
Mechanobiological profiling and regulation of oocyte maturation and embryo preimplantation development.
Morphokinetic analysis of human embryo preimplantation development (computational).
Developing machine-learning classifiers for evaluating the developmental potential of embryos during early preimplantation stages (computational).

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